Radical cholecystectomy without liver resection for peritoneal side early incidental gallbladder cancer.

World J Gastroenterol

Department of Health Sciences (DISS), University of Milan, San Paolo Hospital, Milan 20142, Lombardy, Italy.

Published: August 2024

Gallbladder cancer (GBC) is a rare disease with a poor prognosis. Simple cholecystectomy may be an adequate treatment only for very early disease (Tis, T1a), whereas reoperation is recommended for more advanced disease (T1b and T2). Radical cholecystectomy should have two fundamental objectives: To radically resect the liver parenchyma and to achieve adequate clearance of the lymph nodes. However, recent studies have shown that compared with lymph node dissection alone, liver resection does not improve survival outcomes. The oncological roles of lymphadenectomy and liver resection is distinct. Therefore, for patients with incidental GBC without liver invasion, hepatic resection is not always mandatory.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11362876PMC
http://dx.doi.org/10.3748/wjg.v30.i32.3739DOI Listing

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