Evaluating the efficacy of immunotherapy in gastric cancer: Insights from immune checkpoint inhibitors.

World J Gastroenterol

Institute of Digestive Diseases, Longhua Hospital, China-Canada Center of Research for Digestive Diseases, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China.

Published: August 2024

The emergence of immunotherapy, particularly immune checkpoint inhibitors (ICIs), represents a groundbreaking approach to treating gastric cancer (GC). However, the prognosis of GC patients receiving ICI treatment is influenced by various factors. This manuscript identified sarcopenia and myosteatosis as inde-pendent prognostic factors impacting the outcomes of GC patients treated with ICIs. Additionally, this study introduced a visual predictive model to estimate the prognosis of GC patients. If confirmed by further studies, this observation could provide valuable insights to propel the advancement of personalized clinical medicine and the integration of precision medicine practices.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11362881PMC
http://dx.doi.org/10.3748/wjg.v30.i32.3726DOI Listing

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