Kimura disease: A rare case in Vietnamese woman.

Asia Pac Allergy

Department of Physiology, Pathophysiology & Immunology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.

Published: August 2024

AI Article Synopsis

  • Kimura disease (KD) is a rare, benign inflammatory condition mainly seen in Asian males, marked by tissue masses, swollen lymph nodes, and elevated eosinophil and IgE levels.
  • A unique case of KD was reported in a 31-year-old Vietnamese woman with facial masses and long-standing itching, with biopsy results confirming the diagnosis.
  • The findings suggest that KD can occur in females and emphasize the importance of histopathological examinations for accurate diagnosis, highlighting the need for increased awareness of this condition among Asian women.

Article Abstract

Kimura disease (KD) is a rare benign chronic inflammatory condition that predominantly affects Asian males. It is characterized by subcutaneous tissue masses in the head and neck region, enlarged lymph nodes, increased blood eosinophilia, and elevated serum total IgE levels. In this report, we describe a rare case of KD in a young Vietnamese female. A 31-year-old Vietnamese woman presented to the hospital with 2 masses in the bilateral cheeks and 1 mass behind the left ear that persisted for 15 years, recurrent skin itching, elevated serum total IgE levels, and increased blood eosinophilia. No medical history of the individual or family was recorded. We performed an excision biopsy of the postauricular mass that revealed follicular hyperplasia with small vessel hyperplasia, diffuse infiltration of eosinophils in lymphoid follicles, and several eosinophilic microabscesses. After a comprehensive review, the final diagnosis for this patient was KD and atopic dermatitis comorbidity. In conclusion, KD is not limited to males, as this report demonstrated. The histopathological examination plays an important role in the diagnosis of KD. This case illustrated the characteristic description of KD and highlights the need for awareness of this rare disease in Asian women.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11365659PMC
http://dx.doi.org/10.5415/apallergy.0000000000000134DOI Listing

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