Stone heart syndrome has a complex interaction with digoxin toxicity, where, theoretically, the administration of intravenous calcium can worsen a patient's condition. Research on this subject is conflicting, so it is imperative to approach it cautiously.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11362021PMC
http://dx.doi.org/10.1002/ccr3.9376DOI Listing

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