AI Article Synopsis
- Nephroureterectomy is the standard treatment for high-grade upper tract urothelial carcinoma (UTUC), but exceptions may exist based on individual patient factors.
- A case is presented where a patient with horseshoe kidney and significant kidney issues was successfully treated using a minimally invasive, nephron-sparing method instead of the standard approach.
- This highlights that current treatment guidelines for UTUC may not fit every patient scenario and that personalized treatment plans should be considered in specialized medical centers.
Article Abstract
Nephroureterectomy is currently the criterion-standard treatment for high-grade upper tract urothelial carcinoma (UTUC). Current guidelines and expert opinions propose some exceptions to this approach based on patient characteristics, disease status, and function of the contralateral kidney. We present a rare case of a patient with horseshoe kidney, bilateral large nephrolithiasis, high-grade UTUC in one moiety, and relative parenchymal thinning of the contralateral side. The patient was treated with a percutaneous, minimally invasive, nephron sparing approach. The patient also had intracollecting system instillations of gemcitabine and docetaxel. Minimally invasive percutaneous resection of high-grade UTUC is a safe procedure in select cases. Current guidelines may not apply to all patients; unique scenarios with UTUC may require personalized decision-making and treatment at specialized centers.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11337981 | PMC |
| http://dx.doi.org/10.1097/CU9.0000000000000109 | DOI Listing |
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