AI Article Synopsis
- - Liver fibrosis develops due to changes in the liver tissue caused by chronic inflammation or cell death, leading to changes in the extracellular matrix that can progress to more severe liver diseases like cirrhosis and cancer.
- - Screening for liver fibrosis is becoming increasingly important, as early detection can help address the root causes of liver disease before serious complications arise.
- - Identifying individuals at risk for liver fibrosis is crucial, and initial screening can start with a primary care physician before being referred to a specialist for further evaluation.
Article Abstract
The development of liver fibrosis is the consequence of histological remodeling of the liver parenchyma, reflecting chronic inflammatory liver disease or hepatocyte necrosis. These tissue modifications result in structural changes to the extracellular matrix, predisposing to progression to cirrhosis and hepatocellular carcinoma, whatever the underlying etiology. Recent data demonstrate the potential benefits of screening for hepatic fibrosis, in particular in order to detect and treat the cause of the underlying liver disease as early as possible, which could ultimately lead to the many known complications in cirrhotic patients. Early identification of the population at risk of hepatic fibrosis should precede screening, which may be initiated in the primary care physician's office and continued at a later stage by the specialist.
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| http://dx.doi.org/10.53738/REVMED.2024.20.884.1444 | DOI Listing |
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