AI Article Synopsis
- The study investigates how ingestion of perfluoroalkyl acids (PFAAs) from contaminated food contact materials (FCMs) affects human health, utilizing a toxicity equivalent approach to evaluate multiple PFAAs collectively.* -
- Out of 21 PFAAs analyzed in FCMs, 15 were found, and experiments showed that seven PFAAs migrated into food simulants at varying levels between 0.47 and 46.7 ng/cm.* -
- While most packaged samples posed minimal health risks, 9% indicated a higher risk from perfluorooctanoic acid (PFOA), and overall risk calculations suggested that around 77% of samples may present elevated health risks from P
Article Abstract
Ingestion of perfluoroalkyl acids (PFAAs) via contaminated food contact materials (FCMs) is an important human exposure source. This study adopts a toxicity equivalent approach to evaluate the collective health risk of multiple PFAAs in FCMs. A comprehensive extraction and analysis of 21 PFAAs in FCMs was performed. Among the analyzed substances, 15 PFAAs were detected. Migration experiment using three food simulants revealed the migration range of seven PFAAs from FCMs into the simulant to be 0.47-46.7 ng/cm. The hazard quotient results suggest minimal health risk, except for 9% of packaged samples where perfluorooctanoic acid (PFOA) poses a higher risk. Utilizing PFOA toxic equivalent concentrations, comprehensive risk calculations showed ∼77% of samples potentially posing elevated health risks due to PFAA exposure. This emphasizes the substantial contribution of PFAAs beyond PFOA and underscores the importance of considering them in related assessments. The aggregated risk assessment reflects actual exposure circumstances more accurately.
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| http://dx.doi.org/10.1111/1750-3841.17313 | DOI Listing |
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