Extraction, purification, structural features, and pharmacological properties of polysaccharides from Houttuynia cordata: A review.

Int J Biol Macromol

Shaanxi Key Laboratory of Chinese Medicine Fundamentals and New Drugs Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xi'an 712046, Shaanxi, PR China. Electronic address:

Published: November 2024

AI Article Synopsis

  • - Houttuynia cordata Thunb, often referred to as "Chinese medicine antibiotic," is a plant known for its health benefits in traditional medicine, primarily for its ability to clear heat and eliminate toxins.
  • - Recent research has focused on Houttuynia cordata polysaccharides (HCPs), which have shown a range of bioactivities, including anti-inflammatory, antiviral, antibacterial, antioxidant, and potential anti-cancer properties.
  • - This paper aims to provide a systematic review of HCPs, covering their extraction methods, chemical structures, biological effects, mechanisms of action, and potential applications in therapeutic agents, functional foods, cosmetics, and animal feeds.

Article Abstract

Houttuynia cordata Thunb, also known as "Chinese medicine antibiotic", is a medicine food homology plant. It has functions of clearing heat, eliminating toxins, in folk medicine. The extraction purification and bioactivity of Houttuynia cordata polysaccharides (HCPs) have been of wide interest to researchers in recent years studies. Studies have confirmed that HCPs exhibit various biofunctionalities, such as anti-inflammatory, antiviral, antibacterial, antioxidant, immunomodulatory, regulation of gut microbiota, and gut-lung axis, as well as anti-radiation, and anti-cancer properties. Therefore, a comprehensive systematic review is needed to summarize the recent advances of HCPs and facilitate a better understanding of their biofunctionalities. This paper reviews the research progress of HCPs in extraction and purification methods, chemical structures, biological activities, possible mechanisms of action, and potential application prospects, which can provide some valuable insights and updated information for their further development and application of HCPs in the fields of therapeutic agents, functional foods, cosmetics, animal feeds.

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http://dx.doi.org/10.1016/j.ijbiomac.2024.135230DOI Listing

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