Exosomes in esophageal cancer: Promising nanocarriers in cancer progression, diagnosis, prognosis, and therapy.

Wiley Interdiscip Rev Nanomed Nanobiotechnol

Department of Thoracic Surgery, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, China.

Published: September 2024

AI Article Synopsis

  • - Esophageal cancer (EC) is highly lethal, highlighting the need for better early detection and treatment methods to improve patient outcomes.
  • - Exosomes, which are small vesicles involved in cell communication, show potential as biomarkers for diagnosing and predicting EC, as well as serving as therapeutic tools.
  • - The review discusses how exosomes are related to the progression of EC and explores their applications in its diagnosis, prognosis, and treatment, fitting into the category of nanomedicine for cancer research.

Article Abstract

Esophageal cancer (EC) is one of the most fatal cancers all over the world. Sensitive detection modalities for early-stage EC and efficient treatment methods are urgently needed for the improvement of the prognosis of EC. Exosomes are small vesicles for intercellular communication, mediating many biological responses including cancer progression, which are not only promising biomarkers for diagnosis and prognosis but also therapeutic tools for EC. This review provides an overview of the relationships between exosomes and EC progression, as well as the application of exosomes in the diagnosis, prognosis, and treatment of EC. This article is categorized under: Therapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic Disease.

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Source
http://dx.doi.org/10.1002/wnan.1989DOI Listing

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