AI Article Synopsis
- - The study focused on the effectiveness of radiofrequency ablation (RFA) for treating thyroid nodules classified under Bethesda III that have been identified as benign through molecular profiling (BIII-MPN).
- - Researchers measured outcomes such as volume reduction, symptom improvement, and cosmetic scores for 258 nodules across 192 patients at various intervals after RFA, finding similar improvements between benign nodules and those classified as BIII-MPN.
- - The results indicate that RFA could be a viable treatment for BIII-MPN nodules, but caution is advised due to the risk of not detecting potential malignancies.
Article Abstract
Background: The efficacy of radiofrequency ablation (RFA) in treating thyroid nodules with indeterminate cytology remains less studied. The objective of this study was to determine the efficacy of RFA in treating nodules with Bethesda III that have been molecularly profiled benign (BIII-MPN).
Methods: We included prospectively enrolled patients who underwent RFA for benign and BIII-MPN thyroid nodules. Primary outcome measures were volume reduction ratio (VRR), symptom score (range 0-10), and cosmetic score (range 0-3) at 1, 3, 6, and 12 months after RFA, as well as complication rates.
Results: A total of 258 nodules in 192 patients were included (benign: 238 in 174; BIII-MPN: 20 in 18). The median VRR differed insignificantly, whereas symptom and cosmetic score improvements were similar between two cohorts. BIII-MPN thyroid nodules were associated with lower rates of infection and temporary voice change.
Conclusion: Our preliminary findings suggest that RFA may be a feasible management option for BIII-MPN thyroid nodules. However, appropriate will be important to address the important risk of potentially missed malignancies.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.amjsurg.2024.115929 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!