AI Article Synopsis
- The study focused on creating an NH-Cu-MOF using a simple one-pot method to detect doxorubicin (DOX) through fluorescence.
- The NH-Cu-MOF demonstrated strong fluorescence capabilities, showing a clear relationship between its fluorescence intensity and DOX concentration ranging from 1-100 µmol/L.
- It successfully identified and quantified DOX even in the presence of various other metal ions and antibiotics, achieving a low detection limit of 2.1654 µmol/L, highlighting its potential as an effective fluorescent probe.
Article Abstract
In this study, an NH-Cu-MOF was synthesized using the one-pot method and employed as a fluorescence probe for doxorubicin (DOX) detection. The synthesized NH-Cu-MOF exhibited remarkable fluorescence recognition capabilities for detecting DOX. Within the concentration range of 1-100 µmol/L, a linear relationship was observed between the fluorescence intensity of the NH-Cu-MOF and the DOX concentration. Furthermore, the synthesized NH-Cu-MOF was effectively utilized for highly selective fluorescence quenching recognition and quantitative detection of DOX in the presence of multiple metal ions and other antibiotics. Despite interference from multiple metal ions and antibiotics, DOX was identified and quantified by highly selective fluorescence quenching with a detection limit of 2.1654 µmol/L. These findings underscore the potential of NH-Cu-MOF as a class of "on-off" fluorescent probes for the rapid detection of DOX.
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| http://dx.doi.org/10.1007/s10895-024-03875-7 | DOI Listing |
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