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T-cell large granular lymphocytic leukaemia in rheumatoid arthritis. | LitMetric

AI Article Synopsis

  • T-cell large granular lymphocytic (T-LGL) leukaemia is often linked to autoimmune disorders, with about one-third of patients also having rheumatoid arthritis (RA).
  • A notable portion of RA patients display clonal T-cell patterns, indicating a possible connection between the two conditions.
  • This text discusses a specific case of a patient with RA who was evaluated for low white blood cell count and enlarged spleen, ultimately leading to a diagnosis of T-LGL leukaemia.

Article Abstract

T-cell large granular lymphocytic (T-LGL) leukaemia is frequently associated with an autoimmune phenomenon; approximately one-third of patients have rheumatoid arthritis (RA). Intriguingly, one-third of patients with rheumatoid arthritis exhibit clonal T-cell patterns. Here, we present a patient with RA undergoing evaluation for neutropenia and splenomegaly who was later diagnosed with T-LGL leukaemia.

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Source
http://dx.doi.org/10.1136/bcr-2024-260470DOI Listing

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