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Cutaneous papulo-vesicular eruptions in non-A, non-B hepatitis. | LitMetric

AI Article Synopsis

  • A study found that 36% of patients with non-A, non-B hepatitis developed a relapsing papulo-vesicular rash, mainly on the trunk and arms.
  • The rash occurred alongside general symptoms and elevated liver enzymes, suggesting a connection to skin reactions often seen in enterovirus infections.
  • No specific trends were identified regarding the rash's occurrence based on patient sex, infection type, or patterns of liver enzyme changes.

Article Abstract

A relapsing papulo-vesicular rash with or without pruritus was observed in 54 out of 148 patients (36%) with posttransfusion or sporadic, acute or chronic, non-A, non-B (NANB) hepatitis. The predominant location was the trunk and the anterior surfaces of the upper extremities. The face was affected less often. The eruptive phase was accompanied by general symptoms and increases in aminotransferases and gamma-GT values. The nature of the eruption was consistent with cutaneous reactions as frequently seen in enterovirus infections. No predominance was found for special groups of patients when the skin lesions were correlated to either sex, mode of infection or pattern of transaminase elevation (i.e. monophasic or bi-, and multi-phasic).

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