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A prospective investigation of the prognosis of noncardiac chest pain in emergency department patients. | LitMetric

A prospective investigation of the prognosis of noncardiac chest pain in emergency department patients.

J Psychosom Res

School of Psychology, Université Laval, Québec, Québec, Canada; Research Centre of the Centre intégré de santé et de services sociaux de Chaudière-Appalaches, Lévis, Québec, Canada; Centre de recherche universitaire sur les jeunes et les familles (CRUJeF), Québec, Québec, Canada.

Published: November 2024

AI Article Synopsis

  • This study followed 672 emergency department patients with noncardiac chest pain (NCCP) over two years to track changes in pain intensity, frequency, and overall quality of life.
  • Results showed that while many patients improved, 58.1% were NCCP-free after two years, with four distinct pain progression groups identified: worsening, persistent, limited improvement, and remission trajectories.
  • Notably, those in the remission group had better physical and mental quality of life compared to others, highlighting the need for healthcare focus on the persistent symptoms affecting over 40% of the patients.

Article Abstract

Objectives: This study sought to describe the 2-year evolution of the intensity and frequency of noncardiac chest pain (NCCP), NCCP-related disability and health-related quality of life in a cohort of emergency department (ED) patients. It also aimed to identify and characterize subgroups of patients who share similar NCCP trajectories.

Methods: 672 consecutive patients with NCCP were prospectively recruited in two EDs. NCCP, physical and mental health-related quality of life and pain-related impairment were assessed at baseline and 6 months, 1 year and 2 years after the index ED visit.

Results: Significant reductions in the intensity and frequency of NCCP and in NCCP-related disability were observed over time, with 58.1% of patients being considered NCCP-free at the 2-year follow-up. Four trajectories of NCCP intensity were identified through latent class growth mixture modelling: Worsening Trajectory (6.8%), Persistence Trajectory (20.5%), Limited Improvement Trajectory (13.1%) and Remission Trajectory (59.5%). Physical quality of life was significantly higher in the latter two trajectories at all assessment points. Patients in the Remission Trajectory reported a better mental quality of life and a greater decrease in NCCP-related disability over time than those in the other trajectories.

Conclusions: Over 40% of ED patients with NCCP experienced persistent biopsychosocial morbidity that warrants further clinical attention.

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Source
http://dx.doi.org/10.1016/j.jpsychores.2024.111883DOI Listing

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