Peripheral ulcerative keratitis secondary to tuberculosis: A case report and literature review.

Medicine (Baltimore)

Department of Microbiology, Chengdu Third People's Hospital, Southwest Jiaotong University, Chengdu, Sichuan, China.

Published: August 2024

Rationale: Compared with intraocular tuberculosis, ocular tuberculosis with ocular surface involvement is rare. Corneal involvement in ocular tuberculosis may include interstitial keratitis or peripheral ulcerative keratitis. We report a case of peripheral ulcerative keratitis directly caused by tuberculosis.

Patient Concerns: A 20-year-old man complained of vision loss and pain in the left eye that had lasted for 1 week. A slit lamp examination of the left eye showed a corneal epithelial defect, interstitial corneal edema, and a white irregular infiltrative lesion and ulcer (with the dimension of 2 × 2.5 mm) in the inferior temporal region.

Diagnoses: The corneal ulcer was scraped, and the Mycobacterium tuberculosis deoxyribonucleic acid polymerase chain reaction was positive.

Interventions And Outcomes: After a month of oral antituberculosis treatment, the corneal ulcer resolved, and the intraocular inflammation improved.

Lessons: Peripheral ulcerative keratitis secondary to tuberculosis can be directly caused by M tuberculosis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11365642PMC
http://dx.doi.org/10.1097/MD.0000000000039482DOI Listing

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