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Genetic analyses identify circulating genes related to brain structures associated with Parkinson's disease.
NPJ Parkinsons Dis
January 2025
Shandong Technology Innovation Center of Molecular Targeting and Intelligent Diagnosis and Treatment, Binzhou Medical University, Yantai, China.
Magnetic resonance imaging and circulating molecular testing are potential methods for diagnosing and treating Parkinson's disease (PD). However, their relationships remain insufficiently studied. Using genome-wide association summary statistics, we found in the general population a genetic negative correlation between white matter tract mean diffusivity and PD (-0.
View Article and Find Full Text PDFInfluence of the neck length of urease-powered flask-like colloidal motors on their kinematic behavior.
Soft Matter
January 2025
School of Medicine and Health, Harbin Institute of Technology, XiDaZhi Street 92, Harbin, 150001, China.
Enzyme-powered synthetic colloidal motors hold promising potential for medical applications because of their unique features such as self-propulsion, sub-micrometer size, fuel bioavailability, and structural and functional versatility. However, the key parameters influencing the propulsion efficiency of enzyme-powered colloidal motors still remain unclear. Here, we report the effect of the neck length of urease-powered pentosan flask-like colloidal motors on their kinematic behavior resembling the role of bacterial flagella.
View Article and Find Full Text PDFDirect measurement of brake wear particles from a light-duty vehicle under real-world driving conditions.
Environ Sci Pollut Res Int
January 2025
Research Centre for Energy, Environment and Technology (CIEMAT), Avda. Complutense, 40, 28040, Madrid, Spain.
As tailpipe emissions have decreased, there is a growing focus on the relative contribution of non-exhaust sources of vehicle emissions. Addressing these emissions is key to better evaluating and reducing vehicles' impact on air quality and public health. Tailoring solutions for different non-exhaust sources, including brake emissions, is essential for achieving sustainable mobility.
View Article and Find Full Text PDFHealth Literacy Curricula in Pediatric Residency Programs: A National Survey.
Health Lit Res Pract
January 2025
Objective: Using health literacy informed communication strategies can mitigate health inequities. Despite the high prevalence of limited health literacy among parents and children, pediatricians infrequently use clear communication techniques and further education is imperative. There is minimal literature exploring health literacy curricula in pediatric residencies.
View Article and Find Full Text PDFAnomalous pumping in the non-Hermitian Rice-Mele model.
J Phys Condens Matter
January 2025
School of Physical Sciences, NISER, Jatni, Bhubaneswar, 752050, INDIA.
We study topological charge pumping (TCP) in the Rice-Mele (RM) model with irreciprocal hopping. The non-Hermiticity gives rise to interesting pumping physics, owing to the presence of skin effect and exceptional points. In the static one-dimensional (1D) RM model, we find two independent tuning knobs that can drive the topological transition, namely, non-Hermitian parameter $\gamma$ and system size $N$.
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