Diesel inhalation poisoning represents a rare yet critical medical condition necessitating prompt medical attention due to its potential to induce severe respiratory distress and coagulation dysfunction. The present case study describes the distinctive clinical presentation of a male patient in his early 40s who experienced acute respiratory distress and manifested coagulation factor VII deficiency subsequent to unintentional inhalation of diesel oil during engine repair. The patient demonstrated symptoms including chest tightness and dyspnea, indicative of chemical aspiration pneumonia, alongside an unforeseen coagulation abnormality. Treatment involved rigorous intervention, comprising endotracheal intubation, mechanical ventilation, and administration of pharmacotherapy, including ambroxol, dihydroxypropylline, and methylprednisolone. Moreover, procedural measures, such as repeated bronchoscopic alveolar lavage, pathogen culture, and targeted antibiotic therapy, were employed to mitigate respiratory complications. The patient's clotting disorder was treated with blood transfusions, and he was discharged with improvement. The present case highlights the imperative nature of immediate medical intervention in instances of diesel inhalation to avert further clinical deterioration and unfavorable outcomes. Additionally, it underscores the necessity for expanded research endeavors aimed at elucidating the indirect repercussions of diesel inhalation on the coagulation cascade, an area that remains relatively underexplored within the medical literature.
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http://dx.doi.org/10.1177/03000605241277378 | DOI Listing |
Front Pharmacol
January 2025
Department of Physiology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.
Introduction: Exposure to particulate matter ≤2.5 μm in diameter (PM) is associated with adverse respiratory outcomes, including alterations to lung morphology and function. These associations were reported even at concentrations lower than the current annual limit of PM.
View Article and Find Full Text PDFJ Agromedicine
January 2025
Permanent Representation of Spain to the EU, Brussels, Belgium.
Objective: The fisheries sector is essential to the economies of developing countries, but it is a contributor to greenhouse gas emissions. Although emissions can be substantially reduced through energy efficiency measures, compliance with the Paris Agreement of 2015 requires further action through national frameworks for the decarbonization of fishing vessels. The objective of this paper is to explain the impact in greenhouse gas emissions from fishing vessels, discuss the possible regulatory indexes that could be made applicable to fishing vessels and how these ships can transition to alternative and low carbon fuels, identifying the main challenges in view of accident analysis and inspections.
View Article and Find Full Text PDFEnviron Int
December 2024
School of Population and Public Health, Faculty of Medicine, University of British Columbia, Vancouver, Canada; Department of Medicine, Division of Respiratory Medicine, Air Pollution Exposure Lab, Chan-Yeung Centre for Occupational and Environmental Respiratory Disease, University of British Columbia, Vancouver, Canada. Electronic address:
Background: Mounting evidence links exposure to traffic-related air pollution (TRAP) to impairment in cognitive functioning.
Objectives: To determine if short-term, controlled exposure to diesel exhaust (DE) adversely affects one or more cognitive function domains.
Methods: We carried out a double-blinded crossover design with 28 healthy, adult volunteers.
Environ Int
November 2024
Department of Civil and Environmental Engineering, Hong Kong Polytechnic University, Hong Kong, China.
A typical industrial park in the upper reaches of the Yangtze River Economic Belt, which is 70 km from the Chongqing urban center, was used to investigate the occurrence and exposure of harmful volatile organic compounds (VOCs). An exposure risk method and a risk-oriented source apportionment approach were performed to assess the inhalation risks and apportion VOC sources, respectively. The quantitative relationships between risk factors and pollution sources were established, identifying key pathogenic and odorous VOCs.
View Article and Find Full Text PDFEnviron Health (Wash)
June 2024
Division of Environment and Sustainability, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong 000000, China.
Toxic air pollutants (TAPs) are a class of airborne chemicals known or suspected to cause serious health issues. This study, applying positive matrix factorization and inhalation unit risk estimates of TAPs, quantifies the changes in significant sources contributing to inhalation cancer risks (ICRs) from 2000 to 2020 in Hong Kong, China. Total ICR decreased from 1701 to 451 cases per million between 2000-2004 and 2016-2020, largely attributed to the reduction in diesel particulate matter (DPM), gasoline and solvent use-related volatile organic compounds (VOCs), and coal/biomass combustion-related polycyclic aromatic hydrocarbons and metal(loid)s.
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