AI Article Synopsis
- B-cell epidermotropism is a rare occurrence in skin lymphomas, typically seen in systemic lymphomas like splenic marginal zone lymphoma.
- This type of lymphoma can present with skin symptoms before other signs, such as an enlarged spleen, and may involve bone marrow or blood.
- The case discussed highlights the importance for clinicians to recognize this feature, as it may indicate further disease spread and necessitate more thorough initial staging.
Article Abstract
B-cell epidermotropism is an exceptional finding in cutaneous lymphomas. The few cases previously described in the literature mostly correspond to systemic lymphomas, with the most frequent being splenic marginal zone lymphoma. This lymphoma can manifest as a cutaneous eruption preceding the splenomegaly, with systemic involvement demonstrated by bone marrow and/or peripheral blood. This presentation is known as epidermotropic B-cell lymphoma. Herein, we present a new case that emphasizes B-cell epidermotropism as a feature that should alert the clinician of the possibility of a secondary involvement and, consequently, prompt them to expand the recommended initial staging.
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| http://dx.doi.org/10.1111/ijd.17448 | DOI Listing |
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