AI Article Synopsis

  • - The study examined the relationship between sex and the need for urgent dialysis within 30 days of admission for acute aortic dissection (AD) in nearly 80,000 cases in Japan from 2010 to 2020.
  • - Researchers found that women had a significantly lower risk of requiring urgent dialysis compared to men for both types of AD (type A and type B).
  • - Specifically, the analysis showed a subdistribution hazard ratio of 0.58 for women with type A AD and 0.49 for type B AD, indicating a protective effect of being female in terms of dialysis risk.

Article Abstract

The global outcome of acute aortic dissection (AD) remains poor, with a high risk of the need for urgent dialysis. This study aimed to clarify the association between sex and the requirement for urgent dialysis within 30 days after admission among patients with AD. This study included 79,998 cases who were hospitalized due to AD in Japan from 2010 to 2020 using an administrative claims database. The association between the risk of urgent dialysis and sex was investigated using the Fine and Gray model. Patients were classified into two groups based on the Stanford classification: type A AD (TAAD) and type B AD (TBAD). The lower subdistribution hazard ratio (SHR) in women was observed in both groups: TAAD (SHR: 0.58, 95% confidence interval [CI]: 0.54-0.62); TBAD (SHR: 0.49, 95% CI: 0.41-0.58). Our study revealed that women had a lower risk of requiring urgent dialysis than men in TAAD and TBAD.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11357881PMC
http://dx.doi.org/10.1016/j.isci.2024.110577DOI Listing

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