AI Article Synopsis
- About 25% of the population has a patent foramen ovale (PFO), which is usually asymptomatic, but it can sometimes cause right-to-left shunt (RLS)-mediated hypoxaemia, a rare condition.
- In a case involving a 73-year-old woman, her oxygen levels significantly improved from 87% to 98% after undergoing percutaneous PFO closure due to her progressive difficulty breathing.
- While most PFOs don't cause problems, RLS-mediated hypoxaemia can occur even in older adults, and percutaneous closure is a safe and effective treatment that provides quick relief.
Article Abstract
Background: Approximately 25% of the general population has a patent foramen ovale (PFO) that remains asymptomatic in the vast majority. Right-to-left shunt (RLS)-mediated hypoxaemia is a rare associated condition of PFO.
Case Summary: This report describes a case of percutaneous PFO closure for hypoxaemia in a 73-year-old patient showing immediate clinical benefit. She experienced progressive dyspnoea on exertion requiring oxygen therapy. SaO2 was 87% at rest without oxygen therapy, which increased to 98% after percutaneous PFO closure.
Discussion: Most PFOs remain clinically insignificant but RLS-mediated hypoxaemia is a rare phenomenon that can occur even at advanced age. Percutaneous PFO closure is a safe and effective therapy option that provides immediate improvement of hypoxaemia.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11358635 | PMC |
| http://dx.doi.org/10.1093/ehjcr/ytae415 | DOI Listing |
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