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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11356591 | PMC |
| http://dx.doi.org/10.32481/djph.2024.08.02 | DOI Listing |
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Patient-derived xenografts (PDXs) provide a clinically relevant method for recapitulating tumor-involved cell types and the tumor microenvironment, which is essential for advancing knowledge of breast cancer (BC). Additionally, PDX models enable the study of BC systemic effects, which is not possible using in vitro models. Traditional methods for implanting BC xenografts typically involve anesthesia and sterile surgical procedures, which are time-consuming, invasive, and limit the scalability of PDX models in BC research.
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