Animal amino acid sensor - A review.

Anim Biosci

School of Life Science, Jiangsu Normal University, Jiangsu 221116, China.

Published: February 2025

AI Article Synopsis

  • Amino acids are crucial for cell growth and metabolism, and their detection is managed by the mTORC1 complex in mammals.
  • The exact molecular processes of how amino acids are sensed and how that information is sent to mTORC1 remain largely unclear.
  • The paper discusses the identified amino acid sensors, their structures and functions, and explores how these sensors might affect development in livestock production.

Article Abstract

Cell growth and metabolism necessitate the involvement of amino acids, which are sensed and integrated by the mammalian target of rapamycin complex 1 (mTORC1). However, the molecular mechanisms underlying amino acid sensing remain poorly understood. Research indicates that amino acids are detected by specific sensors, with the signals being relayed to mTORC1 indirectly. This paper reviews the structures and biological functions of the amino acid sensors identified thus far. Additionally, it evaluates the potential role these sensors play in the developmental changes of the livestock production.

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Source
http://dx.doi.org/10.5713/ab.24.0366DOI Listing

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