Vulvar cancer, although rare, poses significant challenges in diagnosis and treatment because of its histopathologic complexities and nuances. This paper reviewed key aspects of the management of vulvar cancer, focusing on histopathologic diagnosis, margin status interpretation, lymph node involvement assessment, and ongoing clinical trials.
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Vulvar keratoacanthoma may be a malignant precursor: A case report and literature review.
Gynecol Oncol Rep
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People's Hospital of China Medical University, Department of Gynecology, People's Hospital of Liaoning Province, Shenyang, China.
Background: Keratoacanthoma is a relatively rare skin tumor, with vulvar keratoacanthoma being even more uncommon. Although the majority of keratoacanthomas exhibit a benign course, a subset of cases may show features of malignant potential, such as marginal invasion and recurrence.
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Canadian Association of Radiologists Cancer Diagnostic Imaging Referral Guideline.
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University of Alberta, Edmonton, AB, Canada.
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View Article and Find Full Text PDFThe Labial Adhesion in Postmenopausal Women: A Systematic Review.
Iran J Med Sci
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Department of Urology, Hasheminejad Kidney Center, Iran University of Medical Sciences, Tehran, Iran.
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Prisma Health Cancer Institute, Greenville, SC 29605, USA.
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View Article and Find Full Text PDFTargeted therapy with antibody-drug conjugates (ADCs) has shown promising results in the treatment of various solid tumours. Sacituzumab-govitecan (SG), a humanised anti-Trop2 monoclonal antibody in combination with the cytotoxic topoisomerase I inhibitor SN38, has been approved for the treatment of metastatic triple-negative breast cancer. The treatment approach with SG requires the expression of Trop2 in the tumour cells.
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