AI Article Synopsis
- - The study investigates how microplastics affect oysters by examining their metabolic profiles and protein expressions through various analytical methods after 21 days of exposure.
- - Results showed microplastic exposure led to oxidative stress in oysters, notably decreasing SOD (superoxide dismutase) activity in the lowest concentration tested (0.1 mg/L).
- - Metabolomics revealed that microplastics disrupted several metabolic pathways, impacting amino acid and lipid metabolism, with varying concentrations resulting in different metabolomic responses, providing vital insights for food safety and health risks.
Article Abstract
The underlying toxicity mechanisms of microplastics on oysters have rarely been explored. To fill this gap, the present study investigated the metabolic profile and protein expression responses of oysters to microplastic stress through metabolomics and biochemical analyses. Oysters were exposed to microplastics for 21 days, and the results indicated that the microplastics induced oxidative stress, with a significant decrease in SOD activity in the 0.1 mg/L exposure group. Metabolomics revealed that exposure to microplastics disturbed many metabolic pathways, such as amino acid metabolism, lipid metabolism, biosynthesis of amino acids, aminoacyl-tRNA biosynthesis, and that different concentrations of microplastics induced diverse metabolomic profiles in oysters. Overall, the current study provides new reference data and insights for assessing food safety and consumer health risks caused by microplastic contamination.
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| http://dx.doi.org/10.1016/j.foodchem.2024.140961 | DOI Listing |
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