AI Article Synopsis
- A new environmentally friendly method for creating arylthio and arylamino compounds has been developed without the use of catalysts or metals.
- This process involves a Michael addition of arylthiols and anilines to nitroolefins and uses methanol as the solvent, eliminating the need for purification steps like recrystallization or chromatography.
- Computational studies using density functional theory are consistent with results from single crystal X-ray analysis, supporting the effectiveness of the proposed synthesis method.
Article Abstract
A highly efficient, catalyst-free, metal-free, atom economical green protocol for the synthesis of arylthio/arylamino methylene compounds by a Michael attack of arylthiols and anilines on nitroolefins derived from acenaphthaquinone and isatin has been developed. The method needs methanol as a reaction solvent and does not require any recrystallization, work-up process or column chromatography. ()-Arylthio alkenes and ()-arylamino alkenes were obtained as the sole products. The results obtained from computational studies using density functional theory on ORCA program (B3LYP/def2-SVP level) are in good agreement with the data obtained from the single crystal X-ray analysis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d4ob01330a | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!