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| http://dx.doi.org/10.3389/fimmu.2024.1475294 | DOI Listing |
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Ten-year follow-up of degenerative spinal lesions on radiographs and MRI in axial spondyloarthritis: results of the DESIR (DEvenir des spondylarthropathies indifférenciées récentes) cohort.
Eur Radiol
March 2025
Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Objectives: To investigate the occurrence of spinal degenerative lesions (DL)s in axial spondyloarthritis (axSpA) inception cohort in radiographs and MRI over 10 years (10Y), to assess their changes over time and factors associated with them.
Methods: Whole spine MRI and cervical and lumbar spine radiographs at baseline/5Y/10Y of patients with axSpA from the DESIR cohort were assessed for DLs by three readers. For descriptive analyses, DLs were defined by agreement between ≥ 2/3 readers or using the average of their assessments, at the patient level (≥ 1 lesion/patient).
Development and implementation of the international AIDA network spondylarthritis registry.
Front Med (Lausanne)
February 2025
Department of Medical Sciences, Surgery and Neurosciences, Research Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, University of Siena, Siena, Italy.
During the last decade, spondyloarthritis (SpA) has increasingly been considered a disease at the crossroads between autoimmunity and autoinflammation. Some patients may even present with autoinflammatory-related manifestations, including fever, hidradenitis suppurativa, other neutrophilic dermatoses, and an unusually high increase in inflammatory markers. Therefore, a subgroup of SpA patients may be identified, and specific details about this cluster need to be investigated.
View Article and Find Full Text PDFThe Spondyloarthritides: From Scientific and Therapeutic Immobility to the Forefront of Rheumatology Research.
Mediterr J Rheumatol
December 2024
First Department of Internal Medicine, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis, Greece.
The Assessment of SpondyloArthritis International Society (ASAS) Consensus-Based Expert Definition of Difficult-to-Manage, including Treatment-Refractory, Axial Spondyloarthritis.
Ann Rheum Dis
February 2025
Department of Rheumatology, Leiden University, Leiden, The Netherlands.
Objectives: To develop a consensus-based expert definition of difficult-to-manage (D2M) axial spondyloarthritis (axSpA), incorporating treatment-refractory (TR) disease.
Methods: A literature review was conducted in 2022 to identify potential definitions for D2M/TR axSpA from prior studies, followed by a 2-round Delphi consensus process conducted in 2022 and 2023 to identify components of D2M axSpA. Based on the results of the Delphi process, a draft of the D2M axSpA definition was developed and presented to the expert task force, including patient representation, and, subsequently, to the Assessment of SpondyloArthritis International Society (ASAS) membership for endorsement in January 2024.
Disparities in Diagnosis: A Call for Equity in Radiographic Axial Spondyloarthritis Care.
J Rheumatol
February 2025
J. Kay, MD, Division of Epidemiology, Department of Population and Quantitative Health Sciences, UMass Chan Medical School, and Division of Rheumatology, UMass Memorial Medical Center, Worcester, Massachusetts, USA.
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