AI Article Synopsis

  • The study focuses on understanding the recurrence rate of colorectal polyps in average-risk individuals, emphasizing the importance of colorectal cancer (CRC) in the Middle East and the role of benign adenomas in its development.
  • A total of 237 patients were enrolled, with 102 completing a 3-year follow-up, revealing that a significant percentage developed adenomatous polyps, particularly those with a more complex morphology having a higher chance of recurrence.
  • The findings suggest the need for enhanced colonoscopy screening in areas previously deemed low-risk for CRC and recommend more frequent surveillance for patients showing dysplasia.

Article Abstract

Background: CRC is going to be an important issue in Middle East countries. Also, the main parts of this cancer develop from benign adenomas.

Aim: To understand the recurrence rate of colorectal polyps among average-risk subjects.

Method: In a prospective study, the average-risk patients with colorectal adenoma were enrolled in this study based on inclusion criteria. The patients were consulted annually by an expert gastroenterologist. A control colonoscopy was programmed after three years of follow-up. It was not an obligation to follow our program, and each patient could exit the study at any time. The patient who developed one of the exclusion criteria was also withdrawn from the study by the gastroenterologist of this study.

Results: 237 patients were enrolled in this study. Of them, 102 patients completed their 3-year follow-up. Among these participants, 62 (60.8%) were male and 40 (39.2%) were female, with a mean age of 57.05 ± 12.87 years. Additionally, 20 (19.6%) subjects had adenomatous polyps at the end of the study. Patients with recurrent colorectal polyps tend to be raised in large ones with a tubulovillous morphology. The polyps were more commonly located in the sigmoid colon, rectum. Furthermore, high-grade dysplasia was recorded in 5 patients. Tubulovillous polyp had higher chance of recurrence than patients with tubular polyp.

Conclusion: We believe the colonoscopy screening needs to be set up in regions previously considered low-risk for CRC. Also, it may be valuable to control colonoscopy for less than three years in patients with dysplasia.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11495456PMC
http://dx.doi.org/10.31557/APJCP.2024.25.8.2823DOI Listing

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