Plaque control is especially important during orthodontic treatment because areas of the teeth near brackets and wires are difficult to clean with a toothbrush, resulting in debris buildup of food or dental plaque, thus causing caries and periodontal disease. The objective of this study was to evaluate the antimicrobial properties of silver nanoparticles (AgNPs), titanium dioxide nanoparticles (TiONPs), and silver/titanium dioxide nanoparticles (Ag/TiONPs), synthesized on the surface of α-alumina ceramic brackets. The AgNPs and TiONPs were synthesized by a simple chemical method, and these were characterized by XRD, SEM, and XPS TEM; the antimicrobial activity was tested against and by diffusion test. The results of this study demonstrated that by this simple chemical method, silver and titanium dioxide nanoparticles can be synthesized on the surface of α-alumina esthetic brackets, and these NPs possess good antimicrobial activity and the possibility of reducing dental caries, periodontal disease, and white spot generated during orthodontic treatment.
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http://dx.doi.org/10.3390/microorganisms12081583 | DOI Listing |
Alzheimers Dement
December 2024
Ecole polytechnique - CNRS UMR7654, Palaiseau, Ile-de-France, France; Université Paris Cité - Inserm UMR-S1124, Paris, Ile-de-France, France.
Alzheimer's disease (AD) is the most common dementia in humans that today concerns 50 million individuals worldwide and will affect more than 100 million people in 2050. Except for familial AD cases (<5% of AD patients) for which AD pathology connects to mutations in critical genes involved in the processing of the amyloid precursor protein into neurotoxic Aß peptides, it remains unknown what provokes the overproduction and deposition of Aß peptides in the brain of sporadic AD cases (>95% of AD patients). Some nanosized materials, e.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Medical Physics, Faculty of Medicine, University of Medical Sciences, Mashhad, Iran.
X-ray induced photodynamic therapy (XPDT) utilizes self-lighting nanoparticles to combine the benefits of radiotherapy and photodynamic therapy. These nanomaterials transform X-ray to visible light that can be absorbed by nearby photosensitizers and in the presence of surrounding oxygen molecules generates reactive oxygen species, which are very toxic to the cells. Despite many studies conducted on modelling XPDT, little focused on the contribution of each component as well as their synergy effects.
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January 2025
Department of Parasitology and Mycology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Medical and surgical treatments for cystic echinococcosis (CE) are challenged by various complications. This study evaluates in vitro protoscolicidal activity of piperine-loaded mesoporous silica nanoparticles (PIP-MSNs) against protoscoleces of Echinococcus granulosus. MSNs were prepared by adding tetraethyl orthosilicate to cetyltrimethylammonium bromide and NaOH, and then loaded with PIP.
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January 2025
Department of Horticultural Science, Faculty of Agriculture, University of Maragheh, Maragheh, 55181-83111, Iran.
Salinity is one of the predominant abiotic stressors that reduce plant growth, yield, and productivity. Ameliorating salt tolerance through nanotechnology is an efficient and reliable methodology for enhancing agricultural crops yield and quality. Nanoparticles enhance plant tolerance to salinity stress by facilitating reactive oxygen species detoxification and by reducing the ionic and osmotic stress effects on plants.
View Article and Find Full Text PDFNat Commun
January 2025
School of Environmental Science and Technology, Dalian University of Technology, Dalian, China.
Efficient detection methods are needed to monitor nitrogen dioxide (NO), a major NO pollutant from fossil fuel combustion that poses significant threats to both ecology and human health. Current NO detection technologies face limitations in stability and selectivity. Here, we present a transition metal nitride sensor that exhibits exceptional selectivity for NO, demonstrating a sensitivity 30 times greater than that of the strongest interfering gas, NO.
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