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Unveiling the Broad-Spectrum Virucidal Potential of Purified Clinoptilolite-Tuff. | LitMetric

Unveiling the Broad-Spectrum Virucidal Potential of Purified Clinoptilolite-Tuff.

Microorganisms

GLOCK Health, Science and Research GmbH, 2232 Deutsch-Wagram, Austria.

Published: August 2024

AI Article Synopsis

Article Abstract

Due to its remarkable surface properties, natural clinoptilolite-tuff interacts with a variety of biochemical, pharmaceutical, chemical, and microbiological entities, including human viruses. In the present work, the virucidal activity of purified clinoptilolite-tuff (PCT) was investigated using a variety of viruses, differing in their structure and composition. Influenza A virus, Herpes Simplex virus, Rhinovirus, and Parvovirus were chosen to represent enveloped and non-enveloped viruses with RNA and DNA genomes. Beside human viruses, Canine Parvovirus and bacteriophages T4 and MS2 were used to represent animal and bacterial viruses, respectively. The virucidal activity of PCT was quantified by examining the residual viral activity on susceptible cell lines upon incubation with PCT. A wide range of antiviral efficiencies was observed, ranging from up to 99% for Herpes Simplex virus to no activity for Rhinovirus and both bacteriophages. This study reveals that the virucidal potential of PCT is not universal and depends on a complex set of factors including virus structure and medium composition. The environmental and medical implications of this research are discussed for uses such as wastewater treatment or wound healing.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11356225PMC
http://dx.doi.org/10.3390/microorganisms12081572DOI Listing

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