This paper comprehensively discusses the fabrication of bionic-based ultrafast laser micro-nano-multiscale surface structures and their performance analysis. It explores the functionality of biological surface structures and the high adaptability achieved through optimized self-organized biomaterials with multilayered structures. This study details the applications of ultrafast laser technology in biomimetic designs, particularly in preparing high-precision, wear-resistant, hydrophobic, and antireflective micro- and nanostructures on metal surfaces. Advances in the fabrications of laser surface structures are analyzed, comparing top-down and bottom-up processing methods and femtosecond laser direct writing. This research investigates selective absorption properties of surface structures at different scales for various light wavelengths, achieving coloring or stealth effects. Applications in dirt-resistant, self-cleaning, biomimetic optical, friction-resistant, and biocompatible surfaces are presented, demonstrating potential in biomedical care, water-vapor harvesting, and droplet manipulation. This paper concludes by highlighting research frontiers, theoretical and technological challenges, and the high-precision capabilities of femtosecond laser technology in related fields.
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http://dx.doi.org/10.3390/ma17164014 | DOI Listing |
Dalton Trans
January 2025
DICATECh, Politecnico di Bari, Bari, I-70125, Italy.
This systematic study delves into the synthesis and characterization of robust bi-functional aminopropyl-tagged periodic mesoporous organosilica with a high loading of small imidazolium bridges in its framework (PrNH@R-PMO-IL, ∼2 mmol g of IL). The materials proved to be a reliable and enduring support for the immobilization of Ru species, demonstrating strong performance and excellent selectivity in the -bromination of various derivatives of 2-phenylpyridine compounds and other heterocycles, showcasing its effectiveness and robust nature. The synthesized materials were thoroughly characterized to determine their structural properties, such as pore size distribution, loading of organic groups, and surface area, using various analytical techniques.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Institut de recherches cliniques de Montréal (IRCM), Montréal, QC, Canada.
Background: Soluble Aβ oligomers (AβOs) induce synapse dysfunction, leading to cognitive impairment and memory deficits in Alzheimer's disease (AD). Our laboratory and several research groups characterized neurexin family members' physiological roles, pivotal synaptic adhesion molecules for development, plasticity, and maintenance. Beyond their normal functions, we found neurexins binding to AβOs causes AβO-induced neurexin dysregulation.
View Article and Find Full Text PDFJ Cell Biol
March 2025
Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, China.
Many cancer cells exhibit increased amounts of paucimannose glycans, which are truncated N-glycan structures rarely found in mammals. Paucimannosidic proteins are proposedly generated within lysosomes and exposed on the cell surface through a yet uncertain mechanism. In this study, we revealed that paucimannosidic proteins are produced by lysosomal glycosidases and secreted via lysosomal exocytosis.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Cleveland Clinic Lerner Research Institute, Cleveland, OH, USA.
Background: Alzheimer's disease (AD) hallmarks are amyloid plaques and tau tangles. APOE and TREM2 are the strongest genetic risk factors for AD. Triggering receptor expressed on myeloid cells 2 (TREM2) is increasingly recognized to play a central role in amyloid beta clearance and microglia activation in AD.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Harvard Medical School and Brigham & Women's Hospital, Boston, MA, USA.
SORL1 (SORLA, LR11) is a large (2214 residue), multi-domain type 1 integral membrane protein that is the product of the SORL1 gene. In neurons, where it is highly expressed, SORL1 functions as both a substrate of and a cargo receptor for the retromer multi protein complex that is a master regulator of protein trafficking out of the early endosome. The SORL1-Vps26b retromer, in particular, is dedicated to the recycling of cell surface proteins, including APP and AMPA receptor subunit GLUA1, back to the plasma membrane.
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