Immature citruses are an important resource for the pharmaceutical industry due to their high levels of metabolites with health benefits. In this study, we used untargeted liquid chromatography-mass spectrometry (LC-MS) metabolomics to investigate the changes associated with fruit size in immature citrus fruits in the first weeks of growth. Three orange cultivars ( 'Navel', 'Valencia', and 'Valencia Late') and a mandarin ( 'Fremont') were separated into eight fruit sizes, extracted, and analyzed. Statistical analyses revealed a distinct separation between the mandarin and the oranges based on 56 metabolites, with an additional separation between the 'Navel' orange and the 'Valencia' and 'Valencia Late' oranges based on 21 metabolites. Then, metabolites that evolved significantly with fruit size growth were identified, including 40 up-regulated and 31 down-regulated metabolites. This study provides new insights into the metabolite modifications of immature and in the first weeks of growth and emphasizes the significance of including early sampled fruits in citrus maturation studies.
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http://dx.doi.org/10.3390/molecules29163718 | DOI Listing |
Medicine (Baltimore)
January 2025
Dianjiang People's Hospital of Chongqing, Chongqing, China.
This study investigates the impact of twin intrahepatic cholestasis in pregnancy (ICP) in different chorionicity scenarios on pregnancy outcome and risk factors. This retrospective study was designed to investigate the association between ICP and pregnancy outcomes and associated risk factors. Logistic regression analysis was used to verify the correlation between ICP and pregnancy outcome and the associated risk factors with the risk of ICP.
View Article and Find Full Text PDFVet Med Sci
January 2025
Veterinary Clinic for Reproductive Medicine and Neonatology, Justus-Liebig University of Giessen, Giessen, Hessen, Germany.
Background: Sheep's tail docking is a widespread practice, which is banned or critically discussed in some countries to improve animal welfare.
Objective: The aim was to determine the influence of breeding for short-tailedness (ST) or long-tailedness (LT) in sheep on the development of reproduction parameters and lamb performance.
Method: One hundred forty-nine ewes were mated with four rams according to tail length.
Adv Skin Wound Care
January 2025
Öznur Tiryaki, PhD, RN, is Associate Professor, Faculty of Health Sciences, Department of Midwifery, Sakarya University, Sakarya, Turkey. Hamide Zengin, PhD, RN, is Associate Professor, Faculty of Health Science, Department of Pediatric Nursing, Eskişehir Osmangazi University, Eskişehir, Turkey. Also at Sakarya University, Nursan Çınar, PhD, RN, is Professor, Faculty of Health Sciences, Department of Pediatric Nursing; Meltem Karabay, MD, is Associate Professor, Faculty of Medicine, Research and Training Hospital of Sakarya, Division of Neonatology, Department of Pediatrics; İbrahim Caner, MD, is Professor, Faculty of Medicine, Research and Training Hospital of Sakarya, Division of Neonatology, Department of Pediatrics; and Ertuğrul Güçlü, MD, is Professor, Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology.
Objective: To determine the effects of sunflower seed oil and coconut oil on the skin integrity and weight gain of preterm infants in the neonatal ICU.
Methods: In this randomized controlled trial, 66 preterm neonates (34-37 weeks' gestation) in the neonatal ICU of a training and research hospital were equally divided into three groups: sunflower seed oil, coconut oil, and control. The weights of neonates in all three groups were measured at admission to the neonatal ICU, at discharge, and at 1 month postdischarge.
Eur J Microbiol Immunol (Bp)
January 2025
1Department of Infectious Diseases, John Hunter Hospital, New Lambton Heights, NSW 2305, Australia.
Interferon-gamma (IFN-γ) autoantibody syndrome is an emerging clinical entity that has been associated with disseminated non-tuberculous mycobacterial infection (dNTM) particularly in healthy young people, a population not previously thought to be at particular risk. A 29-year-old South-East Asian man presented with several weeks of fever, cough, lymphadenopathy, and constitutional symptoms while working on an international cargo ship, deteriorating rapidly with a sepsis-like syndrome. Eventually lymph node and sputum cultures revealed a diagnosis of dNTM infection with growth of both Mycobacterium persicum and Mycobacterium abscessus.
View Article and Find Full Text PDFVet Med Sci
January 2025
Department of Agricultural Biotechnology, Faculty of Agriculture, University of Kırşehir Ahi Evran, Kırşehir, Türkiye.
Background And Objective: This study aimed to determine the effects of in ovo formula product injection on hatching parameters, chick quality, small intestinal development and ileum histology of breeder hen eggs.
Methods: A total of 400 fertilised eggs were obtained from the Atak-S parent flock at 42 weeks of age for the experiment. The experiment was designed in two groups: a control group (C), in which no injection was performed, and the other group in which a solution containing formula products at concentrations of 1.
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