In any Bayesian computations, the first step is to derive the joint distribution of all the unknown variables given the observed data. Then, we have to do the computations. There are four general methods for performing computations: Joint MAP optimization; Posterior expectation computations that require integration methods; Sampling-based methods, such as MCMC, slice sampling, nested sampling, etc., for generating samples and numerically computing expectations; and finally, Variational Bayesian Approximation (VBA). In this last method, which is the focus of this paper, the objective is to search for an approximation for the joint posterior with a simpler one that allows for analytical computations. The main tool in VBA is to use the Kullback-Leibler Divergence (KLD) as a criterion to obtain that approximation. Even if, theoretically, this can be conducted formally, for practical reasons, we consider the case where the joint distribution is in the exponential family, and so is its approximation. In this case, the KLD becomes a function of the usual parameters or the natural parameters of the exponential family, where the problem becomes parametric optimization. Thus, we compare four optimization algorithms: general alternate functional optimization; parametric gradient-based with the normal and natural parameters; and the natural gradient algorithm. We then study their relative performances on three examples to demonstrate the implementation of each algorithm and their efficiency performance.
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http://dx.doi.org/10.3390/e26080707 | DOI Listing |
ACS Nano
January 2025
Department of Physics and Astronomy, University of Manitoba, Winnipeg R3T 2N2, Canada.
Theory and simulations are used to demonstrate implementation of a variational Bayes algorithm called "active inference" in interacting arrays of nanomagnetic elements. The algorithm requires stochastic elements, and a simplified model based on a magnetic artificial spin ice geometry is used to illustrate how nanomagnets can generate the required random dynamics. Examples of tracking and PID control are demonstrated and shown to be consistent with the original stochastic differential equation formulation of active inference.
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Methods: This was a prospective observational cohort study of consecutive, non-traumatic patients with chest pain.
Sci Rep
January 2025
Department of Computer Science and Information Technology, Benazir Bhutto Shaheed University Lyari, Karachi, 75660, Pakistan.
Deep learning-based medical image analysis has shown strong potential in disease categorization, segmentation, detection, and even prediction. However, in high-stakes and complex domains like healthcare, the opaque nature of these models makes it challenging to trust predictions, particularly in uncertain cases. This sort of uncertainty can be crucial in medical image analysis; diabetic retinopathy is an example where even slight errors without an indication of confidence can have adverse impacts.
View Article and Find Full Text PDFMach Learn
October 2024
Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, 55455, MN, USA.
Data for several applications in diverse fields can be represented as multiple matrices that are linked across rows or columns. This is particularly common in molecular biomedical research, in which multiple molecular "omics" technologies may capture different feature sets (e.g.
View Article and Find Full Text PDFHeliyon
December 2024
Higher Institute for Applied Sciences and Technology (HIAST), Damascus, P.O.Box 31983, Syria.
The precision and safety of robotic applications rely on accurate robot models. Bayesian Neural Networks (BNNs) offer the capability to acquire intricate models and provide insights into inherent uncertainties. While recent studies have successfully employed machine learning to predict the Forward Geometric Model (FGM) of a 6-DOF (degrees of freedom) parallel manipulator, traditional methods lack predictive uncertainty estimation.
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