AI Article Synopsis
- - Scabies is a common skin infestation caused by parasites, often seen in crowded living conditions, and can lead to serious skin infections and kidney issues in both kids and adults.
- - Treatment typically involves a combination of Ivermectin (an oral medication) and sulfur-based ointments, although caution is needed for patients with kidney problems because Ivermectin can be harmful to the kidneys.
- - A case report details two brothers with scabies who developed severe skin infections and acute kidney problems, but fortunately, their skin healed and kidney function normalized after treatment.
Article Abstract
Scabies is a parasitic infestation of the skin with high prevalence in crowded spaces. In some instances, scabies becomes the underlying factor for complicated skin-borne opportunistic pathogens infections in both children and adults. Geographic area and socio-economic factors are determinants of the endemic pattern of this disease. Currently, the treatment of scabies has been under special attention. A combination of oral therapy with Ivermectin and sulfur-based ointments are the gold standard. However, caution is required in patients with kidney impairment. The renal involvement in children with scabies is mainly caused by acute glomerulonephritis. The severity of the nephritic syndrome can lead to other complications. Also, Ivermectin possesses a nephrotoxic effect. Severe hypertension can lead to neurological complications. The aim of our case report is to present two unusual complications in brothers with scabies. We report the cases of two brothers with scabies who presented with severe skin infection that developed acute post infectious glomerulonephritis (APIGN). In addition, one of the brothers presented with posterior reversible encephalopathy syndrome (PRES). The other one developed acute tubule-interstitial acute kidney injury following Ivermectin administration. The evolution of skin lesions was favorable, and kidney function returned to normal in both brothers.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11352969 | PMC |
| http://dx.doi.org/10.3390/children11080981 | DOI Listing |
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