AI Article Synopsis
- * The review discusses four key mechanisms of angiogenesis: sprouting, loop formation, coalescent, and intussusception.
- * The authors identify numerous unresolved questions and contradictions in the field and suggest new models to better explain angiogenesis processes.*
Article Abstract
Angiogenesis, or the development of blood vessels by growing from already-formed vessels, is observed in embryonic development, physiological cyclical processes such as wound healing, the encapsulation of foreign bodies, tumor growth, and some other situations. In this review, we analyze the cellular mechanisms of angiogenesis, namely, angiogenesis by sprouting, ansiform (by loop formation) angiogenesis, coalescent angiogenesis, and angiogenesis by intussusception (splitting the capillary into two channels). The analysis of data revealed a lot of unanswered questions and contradictions. Here, we propose several new models of angiogenesis explaining these contradictions.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11354496 | PMC |
| http://dx.doi.org/10.3390/ijms25168575 | DOI Listing |
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