It is shown that Bac megaterium H which has cross-reacting antigens with malignant tumour tissues may influence the time of appearance and growth of tumours, induced by 20-methylcholanthrene in BALB/c mice. The strengthening of tumour growth rate was most distinctly displayed if Bac. megaterium H was injected once 7 days before the methylcholanthrene inoculation.

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