AI Article Synopsis

  • Inositols may play a significant role in the prevention and treatment of various types of cancer by influencing survival and growth pathways, immunity, and oxidative stress.
  • * Many endocrine and neuroendocrine tumors show disrupted pathways that inositols normally help regulate, but the effects of inositol supplementation in these cases are not well understood.
  • * This review aims to outline the molecular mechanisms behind inositols' potential role in these tumors and suggests that they could be used as an additional therapy alongside traditional treatments.

Article Abstract

Inositols have demonstrated a role in cancer prevention and treatment in many kinds of neoplasms. Their molecular mechanisms vary from the regulation of survival and proliferative pathways to the modulation of immunity and oxidative stress. The dysregulation of many pathways and mechanisms regulated by inositols has been demonstrated in endocrine and neuroendocrine tumors but the role of inositol supplementation in this context has not been clarified. The aim of this review is to summarize the molecular basis of the possible role of inositols in endocrine and neuroendocrine tumors, proposing it as an adjuvant therapy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11353224PMC
http://dx.doi.org/10.3390/biom14081004DOI Listing

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