AI Article Synopsis
- Lithium Carbonate is commonly used to treat affective disorders but can lead to various side effects, including a rare condition called Raynaud's phenomenon.
- In a case report, a patient with recurrent depressive disorder developed Raynaud's after starting Lithium, with symptoms disappearing upon stopping the medication and returning when it was resumed.
- While Lithium has been effective for treating vasospastic disorders, this instance demonstrates an unusual negative reaction contrary to its typical efficacy.
Article Abstract
Lithium Carbonate is an effective treatment for affective disorders, but has a range of side effects. This case report highlights a rare side effect of Raynaud's phenomenon following initiation of Lithium therapy in a patient with recurrent depressive disorder. He was commenced on Lithium therapy to treat severe treatment resistant depression with psychotic symptoms when alternative treatments trialled were ineffective. He had no other risk factors or known aetiological causes for development of Raynaud's phenomenon. Symptoms resolved on discontinuation of Lithium and re-emerged on recommencement. Previous case series have shown Lithium effectively treating vasospastic disorders such as cluster headache and Raynaud's phenomenon. However, a paradoxical reaction to those previously described was induced in this case.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11361196 | PMC |
| http://dx.doi.org/10.1186/s12888-024-06007-4 | DOI Listing |
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