AI Article Synopsis
- - The study reviewed charts of children under 21 in New Jersey with Lyme disease who presented with facial nerve palsy, enrolling 122 participants, of which 22.1% had Lyme disease.
- - Key symptoms linked to Lyme disease included fever, male gender, and a combination of headache and fever, with fever being a strong predictor associated with a high odds ratio.
- - These findings indicate that recognizing specific clinical symptoms can aid in the early diagnosis of Lyme disease and prompt treatment, particularly in regions where Lyme disease is common.
Article Abstract
This retrospective chart review examined children with documented Lyme disease serology in New Jersey aged <21 years presenting with facial nerve palsy. The presence of symptoms including tick bite, fever, headache, and arthritis was recorded. Data were categorized based on demographic factors, and multivariate regression was employed. We enrolled 122 children, 54% female (mean age of 11.4 ± 5.1 years); 22.1% had Lyme disease. Fever was a significant predictor of Lyme disease ( = .01), confirmed by multivariate regression (odds ratio [OR] = 16.11, 95% confidence interval [CI] = 2.04, 366.14), as was male gender ( = .01, OR = 3.68, 95% CI = 1.21, 12.89). This association held especially true in Lyme-endemic regions (prevalence ≥ 0.35). The combination of headache with fever was also significantly predictive ( = .01). We found no significant predictive value in the remaining symptoms. These findings suggest that clinical predictors may be useful in diagnosing Lyme disease and initiating early empiric treatment.
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| http://dx.doi.org/10.1177/08830738241272069 | DOI Listing |
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