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The Anti-Obesity Effect of Fish Oil in Diet-Induced Obese Mice Occurs via Both Decreased Food Intake and the Induction of Heat Production Genes in Brown but Not White Adipose Tissue.
Int J Mol Sci
December 2024
Department of Diabetes and Endocrine Medicine, Graduate School of Medicine and Dental Sciences, Kagoshima University, Kagoshima 890-8544, Japan.
Omega-3 (ω-3) polyunsaturated fatty acids in fish oil have been shown to prevent diet-induced obesity in lean mice and to promote heat production in adipose tissue. However, the effects of fish oil on obese animals remain unclear. This study investigated the effects of fish oil in obese mice.
View Article and Find Full Text PDFThe Anti-Inflammatory Effects of Formononetin, an Active Constituent of Var. , via Modulation of Macrophage Autophagy and Polarization.
Molecules
January 2025
College of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, China.
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View Article and Find Full Text PDFActivity of a descending neuron associated with visually elicited flight saccades in Drosophila.
Curr Biol
January 2025
Research Group Neurobiology of Flight Control, Max Planck Institute for Neurobiology of Behavior - caesar, 53175 Bonn, Germany. Electronic address:
Approaching threats are perceived through visual looming, a rapid expansion of an image on the retina. Visual looming triggers defensive responses such as freezing, flight, turning, or take-off in a wide variety of organisms, from mice to fish to insects. In response to looming, flies perform rapid evasive turns known as saccades.
View Article and Find Full Text PDFLiver tissue engineering offers potential in liver transplantation, while the development of hydrogels for scalable scaffolds incorporating natural components and effective functionalities is ongoing. Here, we propose a novel microfluidic 3D printing hydrogel derived from decellularized fish liver extracellular matrix for liver regeneration. By decellularizing fish liver and combining it with gelatin methacryloyl, the hydrogel scaffold retains essential endogenous growth factors such as collagen and glycosaminoglycans.
View Article and Find Full Text PDFA novel human specific lncRNA MEK6-AS1 regulates adipogenesis and fatty acid biosynthesis by stabilizing MEK6 mRNA.
J Biomed Sci
January 2025
Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.
Background: Obesity is becoming one of the major non-communicable diseases with increasing incidence and risks that cannot be ignored. However effective and safe clinical treatment strategies still need to be deeply explored. Increased number and volume of adipocytes lead to overweight and obesity.
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