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Changes in upper airway airflow after rapid maxillary expansion considering normal craniofacial development as a factor: a retrospective study using computer fluid dynamics.
Eur J Orthod
December 2024
Department of General Surgery and Medical-Surgical Specialties, Section of Orthodontics, University of Catania, Policlinico Universitario 'Gaspare Rodolico-San Marco', Via Santa Sofia 78, 95123, Catania, Italy.
Background/objectives: Evidence suggests nasal airflow resistance reduces after rapid maxillary expansion (RME). However, the medium-term effects of RME on upper airway (UA) airflow characteristics when normal craniofacial development is considered are still unclear. This retrospective cohort study used computer fluid dynamics (CFD) to evaluate the medium-term changes in the UA airflow (pressure and velocity) after RME in two distinct age-based cohorts.
View Article and Find Full Text PDFPerioperative anaphylaxis associated with peripheral inserted central catheter: A retrospective observational study.
J Vasc Access
December 2024
Department of Catheter Clinic, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, P.R. China.
Article Synopsis
- - The use of Peripheral Inserted Central Catheters (PICC) for long-term intravenous therapy is rising, but there’s an alarming increase in anaphylaxis cases linked to this procedure.
- - A study at Sun Yat-sen University Cancer Center from January 2021 to August 2023 found that 0.10% of cancer patients experienced anaphylactic reactions during PICC placement, typically lasting around 8 minutes.
- - There is a call for heightened awareness and research among healthcare providers to identify what triggers these reactions and to develop better prevention strategies.
A case report of a 14-year-old male patient with large vessel vasculitis following COVID-19.
Mod Rheumatol Case Rep
December 2024
Department of Pediatrics, University of Tsukuba Hospital, Tsukuba, Ibaraki Prefecture, Japan.
Most reported cases of large vessel vasculitis (LVV) following coronavirus disease 2019 (COVID-19) have involved adults, with paediatric cases being rare. We present the case of a 14-year-old boy who developed LVV following COVID-19. Initially, he presented with fever and cough, and nasopharyngeal polymerase chain reaction testing confirmed COVID-19.
View Article and Find Full Text PDFIn silico prediction of the action of bromelain on PI3K/Akt signalling pathway to arrest nasopharyngeal cancer oncogenesis by targeting phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha protein.
BMC Res Notes
November 2024
Faculty of Resource Science and Technology, Universiti Malaysia Sarawak, Kota Samarahan, Sarawak, 94300, Malaysia.
Article Synopsis
- This research explores the anti-tumor effects of bromelain, derived from pineapple, specifically focusing on its potential impact on nasopharyngeal cancer (NPC).
- Using computational methods, the study examined interactions between bromelain and critical proteins associated with NPC, revealing significant binding affinities with key targets like PIK3CA, EGFR, and mTOR.
- The results indicate that bromelain may influence NPC development by targeting these proteins, particularly PIK3CA, suggesting a possible mechanism through the modulation of the PI3K/Akt signaling pathway.
Radiofrequency Ablation Eustachian Tuboplasty for the Treatment of Chronic Otitis Media with Effusion and Premature Extrusion of the Tympanostomy Tube.
Ear Nose Throat J
October 2024
Department of Otorhinolaryngology-Head and Neck Surgery, 908th Hospital of PLA, Nanchang City, Jiangxi Provice, China.
This study evaluated the effects of radiofrequency ablation (RFA) eustachian tuboplasty on the treatment of chronic otitis media with effusion (COME), and associated complications, in patients with premature extrusion of the tympanostomy tube (TT). Tuboplasty and T-tube reinsertion were performed in 23 ears with COME, a history of premature TT extrusion, and thickened mucus. Tube retention, perforation closure, hearing improvement, and complications were evaluated.
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