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Beyond the desert sands: decoding the relationship between camels, gut microbiota, and antibiotic resistance through metagenomics.
Sci One Health
July 2024
Institute of Applied Microbiology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, Xinjiang Uygur Autonomous Region, China.
Background: Camels, known as the enduring "ships of the desert," host a complex gut microbiota that plays a crucial role in their survival in extreme environments. However, amidst the fascinating discoveries about the camel gut microbiota, concerns about antibiotic resistance have emerged as a significant global challenge affecting both human and animal populations. Indeed, the continued use of antibiotics in veterinary medicine has led to the widespread emergence of antibiotic-resistant bacteria, which has worsened through gene transfer.
View Article and Find Full Text PDFOverexpression of C1orf74 predicts poor outcome and promote cervical cancer progression.
Heliyon
December 2024
Gynecologic Oncology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, Henan, China.
Article Synopsis
- Cervical cancer is a major global health issue, and researchers are focusing on identifying new biomarkers to understand its progression better.
- Chromosome 1 open reading frame 74 (C1orf74) was found to be overexpressed in cervical cancer cases, correlating with poor prognosis and various clinical factors.
- C1orf74 not only promotes cancer growth but is also linked to immune cell infiltration and the MAPK signaling pathway, making it a potential target for improving treatment strategies for cervical cancer.
Ribosome profiling reveals dynamic translational landscape in HEK293T cells following X-ray irradiation.
Genomics
January 2025
Department of Clinical Laboratory of Sir Run-Run Shaw Hospital, and School of Public Health, Zhejiang University School of Medicine, Hangzhou 310058, China. Electronic address:
X-ray irradiation induces widespread changes in gene expression. Positioned at the bottom of the central dogma, translational regulation responds swiftly to environmental stimuli, fine-tuning protein levels. However, the global view of mRNA translation following X-ray exposure remains unclear.
View Article and Find Full Text PDFLand Use Change Consistently Reduces α- But Not β- and γ-Diversity of Bees.
Glob Chang Biol
January 2025
School of Biological Sciences, The University of Hong Kong, Hong Kong, China.
Land use change threatens global biodiversity and compromises ecosystem functions, including pollination and food production. Reduced taxonomic α-diversity is often reported under land use change, yet the impacts could be different at larger spatial scales (i.e.
View Article and Find Full Text PDFA Digital Parenting Intervention With Intimate Partner Violence Prevention Content: Quantitative Pre-Post Pilot Study.
JMIR Form Res
January 2025
UNICEF Jamaica, Kingston, Jamaica.
Background: Intimate partner violence (IPV) and violence against children are global issues with severe consequences. Intersections shared by the 2 forms of violence have led to calls for joint programming efforts to prevent both IPV and violence against children. Parenting programs have been identified as a key entry point for addressing multiple forms of family violence.
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