AI Article Synopsis
- The Japanese Society of Mood Disorders (JSMD) updated its bipolar disorder treatment guidelines in 2011, incorporating new research and aligning with the National Academy of Medicine's standards.
- The guidelines advocate for the use of combination therapy involving mood stabilizers and second-generation antipsychotics, recognizing their effectiveness in treatment.
- However, they face limitations, as mood stabilizers and antipsychotics were grouped together in analysis due to limited specific evidence for individual drugs, yet still offer valuable clinical support for psychiatrists in Japan.
Article Abstract
The Japanese Society of Mood Disorders (JSMD) published treatment guidelines of bipolar disorder in 2011. The present guidelines incorporating new findings were developed to comply to the guidelines of the National Academy of Medicine (NAM) by utilizing systematic reviews and meta-analysis and taking patient and family opinions as well as insights from multiple professional fields into account. They support combination therapy using mood stabilizers and second-generation antipsychotics in many aspects. They also have limitations, including the grouping of mood stabilizers and second-generation antipsychotics when meta-analysis was performed despite their distinct properties, due to the scarcity of drug-specific evidence. Despite the limitations, these guidelines provide clinical decision support for psychiatrists in Japan.
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| http://dx.doi.org/10.1111/pcn.13724 | DOI Listing |
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