[Current Status of Application and Quality Evaluation of Commercial Platelet Pathogen Reduction Technology --Review].

Zhongguo Shi Yan Xue Ye Xue Za Zhi

Provincial Key Laboratory for Transfusion-Transmitted Infectious Diseases, Institute of Blood Transfusion, Chinese Academy of Medical Sciences and Peking Union Medical College, Chengdu 610062, Sichuan Province, China.

Published: August 2024

AI Article Synopsis

  • The text discusses the growing concern for pathogen contamination in platelet transfusions as transfusion medicine advances.
  • It highlights the success of pathogen reduction technology (PRT) in improving platelet safety and summarizes various research efforts related to its application and effectiveness.
  • The paper also suggests ways to enhance blood safety in China through tailored development of PRT products, based on current studies and understanding of PRT mechanisms.

Article Abstract

With the development of transfusion medicine, platelet pathogen contamination is of increasing concern to the industry. Currently, pathogen reduction technology (PRT) has been successfully applied to platelets and achieved good results. This paper provides an overview of the research progress of commercial platelet PRT, a comprehensive analysis of the current application status of platelet PRT, preclinical mechanism studies, clinical cohort studies and alternative or complementary strategies, and makes recommendations to provide a scientific basis for safeguarding blood safety in China and developing platelet PRT products applicable to our national conditions.

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Source
http://dx.doi.org/10.19746/j.cnki.issn.1009-2137.2024.04.050DOI Listing

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