AI Article Synopsis
- Pulmonary alveolar proteinosis (PAP) is usually linked to autoimmune disorders, but this case highlights a rare instance caused by an infection from Bacillus megaterium.
- A 58-year-old woman experienced cough and breathing difficulties for six months, with a CT scan revealing a distinctive "crazy paving" pattern, and B. megaterium was identified through a biopsy.
- This case is significant as it’s the first documented instance of PAP caused by B. megaterium in otherwise healthy individuals, emphasizing the need to consider unusual infections as potential secondary causes of PAP.
Article Abstract
Background: Pulmonary alveolar proteinosis (PAP) is a special clinical presentation mostly associated with autoimmune disorders. Here we report a rare case of PAP secondary to infection of Bacillus megaterium.
Case Presentation: A 58-year-old woman presented with intermittent cough and dyspnea for half a year. Chest CT scan showed "crazy paving" pattern. B. megaterium was identified by percutaneous CT-guided needle biopsy. She continuously received antimicrobial treatment since the diagnosis and follow-up examination suggested great improvement.
Conclusions: To our knowledge, this is the first case of B. megaterium infection presented with PAP pattern in healthy individuals. Attention should be paid on the secondary causes including rare pathogen infection when patients presented with PAP syndrome.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11348727 | PMC |
| http://dx.doi.org/10.1186/s12879-024-09713-2 | DOI Listing |
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