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Cross-validating the electrophysiological markers of early face categorization.

eNeuro

January 2025

Eye and Brain Mapping Laboratory (iBMLab), Department of Psychology, University of Fribourg, 1700 Fribourg, Switzerland

Human face categorization has been extensively studied using event-related potentials (ERPs), positing the N170 ERP component as a robust neural marker of face categorization. Recently, the fast periodic visual stimulation (FPVS) approach relying on steady-state visual evoked potentials (SSVEPs) has also been used to investigate face categorization. FPVS studies consistently report strong bilateral SSVEP face categorization responses over the occipito-temporal cortex, with a right hemispheric dominance, closely mirroring the N170 scalp topography.

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The rapid advancements in the field of genetics have significantly propelled the development of gene therapies, paving the way for innovative treatments of various hereditary disorders. This review focuses on the genetics of ophthalmologic conditions, highlighting the currently approved ophthalmic gene therapy and exploring emerging therapeutic strategies under development. Inherited retinal dystrophies represent a heterogeneous group of genetic disorders that manifest across a broad spectrum from infancy to late middle age.

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During neuronal synaptic transmission, the exocytotic release of neurotransmitters from synaptic vesicles in the presynaptic neuron evokes a change in conductance for one or more types of ligand-gated ion channels in the postsynaptic neuron. The standard method of investigation uses electrophysiological recordings of the postsynaptic response. However, electrophysiological recordings can directly quantify the presynaptic release of neurotransmitters with high temporal resolution by measuring the membrane capacitance before and after exocytosis, as fusion of the membrane of presynaptic vesicles with the plasma membrane increases the total capacitance.

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Rationale And Objectives: This study aimed to evaluate the efficacy of ultrasound (US)-guided local steroid injection in carpal tunnel syndrome (CTS) using shear wave elastography (SWE).

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