AI Article Synopsis

  • Pseudocirrhosis can occur after chemotherapy for breast cancer with liver metastasis, resembling actual liver cirrhosis.
  • A study reports on 5 patients treated with eribulin, a chemotherapy drug, who developed pseudocirrhosis during their treatment.
  • Although liver metastases shrank significantly early on, these patients ultimately experienced poor health outcomes.

Article Abstract

Pseudocirrhosis, which is radiologically and clinically similar to liver cirrhosis, may develop following chemotherapy for breast cancer with liver metastasis. There are few reports of eribulin treatment. We report 5 patients with metastatic or recurrent breast cancer who developed pseudocirrhosis during eribulin treatment. All patients had diffuse liver metastasis, and the liver metastases significantly reduced in size during the early phase of eribulin treatment, when they developed pseudocirrhosis. Subsequently, the patients had poor prognoses.

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