A sulfur-mediated umpolung strategy employing -thiosuccinimides and (EtO)P(O)SH has been developed to synthesize unsymmetrical organophosphorus disulfides (P(O)-S-S motif). A pronucleophile (EtO)P(O)SH, Brønsted acid and phosphorothioate nucleophile, converts -thiosuccinimides into unsymmetrical phosphorus disulfides. This protocol achieves catalyst- and additive-free reaction conditions, uses a renewable solvent (EtOH), and avoids harsh reagents.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/d4ob01099j | DOI Listing |
Publication Analysis
Top Keywords
unsymmetrical phosphorus
8
phosphorus disulfides
8
synthesis unsymmetrical
4
disulfides sulfur-mediated
4
sulfur-mediated umpolung
4
umpolung strategy
4
strategy employing
4
employing -thiosuccinimides
4
-thiosuccinimides etoposh
4
etoposh developed
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!