Primary tubercular osteomyelitis of zygoma: A literature review and case report.

IDCases

Department of Oral and Maxillofacial Surgery, Sharad Pawar Dental College, Datta Meghe Institute of Higher Education and Research, Sawangi, Wardha, Maharashtra 442001, India.

Published: July 2024

Purpose: This study presents a rare case of primary tubercular osteomyelitis of the zygoma, and addresses how combined surgical and medical treatments are effective managing rare presentations of tubercular osteomyelitis in facial bones.

Methods: A 57-year-old man presented with pain and purulent discharge from the right malar region following trauma. Initial treatments with empirical antibiotics had poor response, hence further investigations were done. Comprehensive diagnostic workup included lab tests, Computed tomography with contrast, and histopathological examination. The patient underwent surgical debridement of the zygomatic bone through an intraoral approach, and debrided tissue was sent for microbiological and histopathological examination, which confirmed tubercular osteomyelitis. Post-surgery, the patient was treated with a four-drug anti-tubercular regimen.

Results: Following anti-tubercular therapy, the patient showed significant improvement, with no signs of disease recurrence after a year of follow-up.

Conclusion: Primary tubercular osteomyelitis of the zygoma is extremely rare but should be considered in differential diagnoses of facial swellings and discharging sinuses. This case underscores the importance of a multidisciplinary approach in treating rare presentations of tubercular osteomyelitis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11347050PMC
http://dx.doi.org/10.1016/j.idcr.2024.e02044DOI Listing

Publication Analysis

Top Keywords

tubercular osteomyelitis
24
primary tubercular
12
osteomyelitis zygoma
12
rare presentations
8
presentations tubercular
8
histopathological examination
8
osteomyelitis
6
tubercular
5
zygoma literature
4
literature review
4

Similar Publications

Sacroiliac joint (SIJ) tuberculosis (TB) is an infrequent clinical entity, especially in developed countries. The symptoms are usually non-specific, and therefore it may mimic a variety of degenerative and non-degenerative diseases, hampering the diagnosis. An interesting case of SIJ infection with psoas abscess in a 77-year-old male is presented in the current article.

View Article and Find Full Text PDF

What Is the Accuracy of 16S PCR Followed by Sanger Sequencing or Next-generation Sequencing in Native Vertebral Osteomyelitis? A Systematic Review and Meta-analysis.

Clin Orthop Relat Res

December 2024

Division of Public Health, Infectious Diseases and Occupational Medicine, Department of Medicine, Mayo Clinic College of Medicine and Science, Mayo Clinic, Rochester, MN, USA.

Article Synopsis
  • - Identifying bacteria in native vertebral osteomyelitis is difficult due to slow culture methods and varying accuracy of molecular diagnostics like 16S PCR and metagenomic sequencing, creating uncertainty in their clinical effectiveness.
  • - A study conducted in 2023 reviewed data from January 1970 to June 2023 to evaluate the sensitivity, specificity, and diagnostic odds ratios of these molecular methods in adults suspected of having this condition, excluding certain types of osteomyelitis.
  • - Out of 3403 studies reviewed, 10 were selected for analysis based on strict criteria, ultimately involving 391 patients, revealing moderate risk of bias but good applicability for diagnosing native vertebral osteomyelitis.
View Article and Find Full Text PDF

Mucormycosis of tibia is a highly aggressive fungal infection. It is an uncommon affection especially in immunocompromised host who have more propensity for such affections. The nonhealing ulcer of the left leg in an immunocompromised host status of a 45-year-old male presented with a radiological lytic lesion of the distal lower fourth of tibia.

View Article and Find Full Text PDF
Article Synopsis
  • A case was reported of a woman in her mid-thirties with a long history of pulmonary TB who struggled with left heel pain and mobility issues due to tuberculous OM for three years, despite not showing typical systemic symptoms.
  • Early diagnosis and prompt anti-tubercular treatment are crucial for managing tuberculous OM, as most cases respond well to conservative care, while surgical options are reserved for severe cases.
View Article and Find Full Text PDF
Article Synopsis
  • Tuberculosis of the musculoskeletal system is rare, representing only 1-3% of all TB cases, with isolated cases in the foot being even less common, impacting mainly the spine and large joints.
  • A 55-year-old man misdiagnosed with Charcot foot experienced persistent left foot pain, which eventually led to an MRI revealing joint inflammation and bone damage, identifying Mycobacterium tuberculosis.
  • This case underscores the need for awareness of osteoarticular tuberculosis in immunocompromised patients and highlights the value of a multidisciplinary approach for accurate diagnosis and treatment.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!