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Leishmania sp. can affect the cardiovascular system of dogs - A systematic review of over 80 years.
Vet Parasitol
January 2025
Department of Veterinary Clinic and Surgery, Veterinary School, Federal University of Minas Gerais - UFMG, Belo Horizonte, Minas Gerais, Brazil; National Institute of Science and Technology in NanoBiopharmaceutics (INCT-Nanobiofar), Belo Horizonte, Minas Gerais, Brazil.
Cardiovascular involvement in Leishmania sp. infections still requires further elucidation, with cutaneous and organic changes being more frequently observed. The aim of this study was to conduct a systematic review of cardiovascular involvement in dogs with canine visceral leishmaniasis, considering a publication span of over 80 years.
View Article and Find Full Text PDFBackground: Recent reports suggest increased myocardial iNOS expression leads to excessive protein -nitrosylation, contributing to the pathophysiology of HFpEF. However, the relationship between NO bioavailability, dynamic regulation of protein -nitrosylation by trans- and de-nitrosylases, and HFpEF pathophysiology has not been elucidated. Here, we provide novel insights into the delicate interplay between NO bioavailability and protein -nitrosylation in HFpEF.
View Article and Find Full Text PDFBackground: T cell mediated immunity is reported to play a pathogenic role in cardiac allograft vasculopathy (CAV) in heart transplant (HTx) patients. However, peripheral blood CD8 T cells have not been previously characterized in CAV. This study aimed to identify potentially pathogenic circulating CD8 T cell populations in high grade CAV patients using cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq).
View Article and Find Full Text PDFRole of Social Determinants of Health in COVID-19 Recovery: A Qualitative Study.
JAMA Netw Open
January 2025
Department of Medicine, Duke University, Durham, North Carolina.
Article Synopsis
- Health systems are increasingly focusing on screening for health-related social needs, but the impact of social resources on recovery from illnesses like COVID-19 is still not fully understood.
- A study was conducted through interviews with 24 participants, including patients and caregivers, to explore how social determinants of health (SDOH) influenced COVID-19 recovery.
- Three main themes emerged: innovative social resource mobilization helped recovery, while disruptions in social support networks and mistrust in institutions posed challenges.
Recovery at 30: Integrating Lived Experience Expertise into Mental Health Research in Israel.
Community Ment Health J
January 2025
Department of Social Work, Ben Gurion University of the Negev, Be'er Sheva, Israel.
A major component of recovery is the inclusion of lived experience to transform the culture of Mental Health (MH) services. In Israel lived experience has been increasingly integrated into services through peer roles. However, lived experience knowledge and expertise has not been sufficiently nor systematically integrated into the design of mental health research.
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