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The public health risks of counterfeit pills.
Lancet Public Health
January 2025
Department of Family Community Medicine, University of California, San Francisco, San Francisco, CA, USA.
Synthetic illicit drugs, such as nitazenes and fentanyls, are becoming commonplace in countries around the world, including in Europe, Australia, and Latin America, which raises concern for overdose crises like those seen in North America. An important dimension of the risk represented by synthetic drugs is the fact that they are increasingly packaged in counterfeit pill form. These pills-often indistinguishable from authentic pharmaceuticals-have substantially widened the scope of populations susceptible to synthetic drug overdose in North America (eg, among adolescents experimenting with pills or tourists from the USA seeking psychoactive medications from pharmacies in Mexico).
View Article and Find Full Text PDFUnregulated male sexual enhancement treatments: Perils and pitfalls for patients and providers.
J Am Assoc Nurse Pract
January 2025
Center for AIDS Preventions Studies (CAPS), University of California San Francisco, San Francisco, California.
As the demand for "quick-fixes" and instant gratification intensifies among consumers of the US health care delivery system, health care providers remain essential to ensuring patients receive safe, evidenced-based care. Erectile dysfunction is a common health condition affecting as many as 42% of US men. As such, it is unsurprising that American health care consumers affected by erectile dysfunction (ED) may be tempted by "quick fixes" to ameliorate their symptoms-particularly if such fixes are perceived to be less embarrassing, more accessible, and/or more affordable.
View Article and Find Full Text PDFAdolescents' perceptions, experiences, and reactions to "fake" vaping devices.
Drug Alcohol Depend
December 2024
Center for Tobacco Control Research and Education, University of California San Francisco, 95 Kirkham Street Box 1361, San Francisco, CA 94143, United States.
Article Synopsis
- Vaping among adolescents, particularly with fake devices, poses significant health risks, as highlighted by the 2019-2020 EVALI outbreak.
- Interviews with 47 California teens revealed their awareness of fake vaping products, which they viewed as low-quality and dangerous, learned about through peers and social media.
- Participants felt that the existence of these fake devices was driven by profit, calling for better public messaging and stronger regulations to protect young users.
How 3D printing technologies could undermine law enforcement strategies targeting the production and distribution of designer drugs.
Sci Justice
November 2024
School of Engineering, Ulster University, Belfast, Northern Ireland BT15 1ED, UK. Electronic address:
Article Synopsis
- Counterfeit and designer drugs, particularly those laced with fentanyl, pose significant challenges due to their potency and easy access, affecting families and society at large.
- Legislative efforts to restrict the production machinery have led to successful pill press seizures, but advancements in low-cost milling machines and 3D printing threaten to undermine these gains.
- The text explores the mechanics of pill presses, current strategies to combat drug distribution, and evaluates the future impact of evolving manufacturing technologies on the supply of fentanyl pills.
Development of an Electrochemical Paper-Based Device Modified with Functionalized Biochar for the Screening of Paracetamol in Substandard Medicines.
Molecules
November 2024
School of Agriculture, São Paulo State University (UNESP), Botucatu 18610-034, SP, Brazil.
The global prevalence of counterfeit and low-quality pharmaceuticals poses significant health risks and challenges in medical treatments, creating a need for rapid and reliable drug screening technologies. This study introduces a cost-effective electrochemical paper-based device (ePAD) modified with functionalized bamboo-derived biochar (BCF) for the detection of paracetamol in substandard medicines. The sensor was fabricated using a custom 3D-printed stencil in PLA, designed for efficient production, and a 60:40 (m/m) graphite (GR) and glass varnish (GV) conductive ink, resulting in a robust and sensitive platform.
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